Postdoctoral Fellow

The Murthy laboratory at the University of California at Berkeley is currently looking to hire multiple postdoctoral fellows to work on projects in the areas of mRNA delivery, antisense oligonucleotide delivery and therapeutic genome editing. The Murthy laboratory is located on the U.C. Berkeley campus and housed in the Innovative Genomics Institute (IGI), please see https://innovativegenomics.org/ for details about the IGI. We have active collaborations with numerous faculty at the IGI and also actively collaborate with members of the Gladstone Institute at UCSF. These collaborations are funded by multi-year NIH and private grants and postdocs in the Murthy laboratory have multiple opportunities to interact with world class scientists in all areas of the life sciences. In addition, U.C. Berkeley is located in the Bay Area and has one of the most vibrant biotechnology sectors in the world and the Murthy laboratory has numerous collaborations with biotechnology companies in the Bay area. Finally, U.C. Berkeley has a very strong track record of producing future faculty members and a postdoctoral position at U.C. Berkeley is an ideal place to launch an independent career as a new investigator. Details of the projects in the Murthy laboratory are described below. (1) Next generation lipid nanoparticles (LNPs) for mRNA delivery. This project involves the chemical synthesis of new classes of lipids and their analysis for mRNA delivery after incorporation into LNPs. Please recent papers by the Murthy lab for details of these projects, Zhao et al. Nat Nanotechnol. 2024 Nov;19(11):1702-1711. doi: 10.1038/s41565-024-01765-4, Chen et al. Nat Biotechnol. 2024 Oct 16. doi: 10.1038/s41587-024-02437-3 and Gao et al. ACS Nano. 2024 Nov 5;18(44):30293-30306. doi: 10.1021/acsnano.4c05169. (2) Transfection of the microbiome. This project involves the development of devices or delivery vectors that can transfect the microbiome of mice and cows with oligonucleotides, plasmids or other biomolecules. Candidates need to have significant experience with either small molecule organic synthesis or mammalian cell culture and recombinant protein expression. For more information about the Murthy laboratory please visit: https://murthylab.berkeley.edu.